Rui Henrique Selected Research

Methyltransferases

6/2022	G9a inhibition by CM-272: Developing a novel anti-tumoral strategy for castration-resistant prostate cancer using 2D and 3D in vitro models.
1/2022	Downregulation of m6 A writer complex member METTL14 in bladder urothelial carcinoma suppresses tumor aggressiveness.
8/2021	The component of the m6A writer complex VIRMA is implicated in aggressive tumor phenotype, DNA damage response and cisplatin resistance in germ cell tumors.
3/2020	VIRMA-Dependent N6-Methyladenosine Modifications Regulate the Expression of Long Non-Coding RNAs CCAT1 and CCAT2 in Prostate Cancer.
1/2020	Differential expression of DNA methyltransferases and demethylases among the various testicular germ cell tumor subtypes.
12/2018	The Role of DNA/Histone Modifying Enzymes and Chromatin Remodeling Complexes in Testicular Germ Cell Tumors.
11/2018	The Emerging Role of Epitranscriptomics in Cancer: Focus on Urological Tumors.
5/2015	SMYD3 contributes to a more aggressive phenotype of prostate cancer and targets Cyclin D2 through H4K20me3.
8/2014	Anti-neoplastic properties of hydralazine in prostate cancer.
1/2014	Anti-tumoral effect of the non-nucleoside DNMT inhibitor RG108 in human prostate cancer cells.

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Rui Henrique Research Topics

Disease

131	Neoplasms (Cancer) 02/2024 - 10/2003
58	Prostatic Neoplasms (Prostate Cancer) 03/2024 - 11/2004
32	Carcinogenesis 06/2023 - 01/2006
22	Carcinoma (Carcinomatosis) 01/2023 - 05/2002
21	Renal Cell Carcinoma (Grawitz Tumor) 12/2022 - 04/2007
19	Breast Neoplasms (Breast Cancer) 10/2023 - 02/2004
18	Urinary Bladder Neoplasms (Bladder Cancer) 01/2024 - 12/2010
16	Germ Cell and Embryonal Neoplasms (Germ Cell Tumor) 08/2021 - 02/2005
13	Neoplasm Metastasis (Metastasis) 02/2024 - 01/2017
7	Urologic Neoplasms (Urological Cancer) 09/2023 - 12/2007
7	Colorectal Neoplasms (Colorectal Cancer) 11/2018 - 08/2011
4	Inflammation (Inflammations) 03/2023 - 10/2003
4	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2023 - 12/2019
4	Lung Neoplasms (Lung Cancer) 06/2022 - 12/2013
4	Testicular Germ Cell Tumor 01/2021 - 01/2020
4	Adenocarcinoma 09/2020 - 12/2002
4	Prostatic Intraepithelial Neoplasia 01/2019 - 12/2004
4	Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer) 01/2019 - 08/2015
3	Non-Muscle Invasive Bladder Neoplasms 01/2023 - 01/2020
3	Circulating Neoplastic Cells 12/2022 - 03/2021
3	Abdominal Obesity 10/2022 - 08/2018
3	Kidney Neoplasms (Kidney Cancer) 12/2021 - 01/2011
3	Disease Progression 03/2021 - 10/2019
3	Oxyphilic Adenoma (Oncocytoma) 01/2015 - 07/2007
3	Squamous Cell Carcinoma of Head and Neck 07/2011 - 10/2006
2	Embryonal Carcinoma 02/2024 - 01/2021
2	Fibrosis (Cirrhosis) 03/2023 - 10/2012
2	Residual Neoplasm 01/2023 - 11/2020
2	Esophageal Neoplasms (Esophageal Cancer) 01/2023 - 11/2020
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 10/2022 - 09/2019
2	Fibroadenoma 01/2022 - 05/2008
2	Seminoma 08/2021 - 12/2019
2	Hypoxia (Hypoxemia) 12/2020 - 11/2019
2	Metaplasia 09/2020 - 09/2011
2	Proteinuria 01/2019 - 10/2007
2	Microsatellite Instability 12/2017 - 10/2010

Drug/Important Bio-Agent (IBA)

88	Biomarkers (Surrogate Marker)IBA 03/2024 - 01/2007
32	Proteins (Proteins, Gene)FDA Link 11/2023 - 02/2005
27	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 12/2002
26	MicroRNAs (MicroRNA)IBA 09/2023 - 10/2011
15	Histones (Histone)IBA 01/2024 - 02/2005
13	Messenger RNA (mRNA)IBA 02/2022 - 11/2006
12	EnzymesIBA 12/2021 - 05/2002
11	RNA (Ribonucleic Acid)IBA 01/2024 - 06/2009
11	MethyltransferasesIBA 06/2022 - 05/2011
8	ChromatinIBA 11/2023 - 02/2005
8	Cell-Free Nucleic AcidsIBA 06/2022 - 09/2018
8	Tumor Biomarkers (Tumor Markers)IBA 01/2022 - 01/2007
7	Cisplatin (Platino)FDA LinkGeneric 02/2024 - 01/2017
7	Androgen Receptors (Androgen Receptor)IBA 11/2023 - 10/2011
7	Phenobarbital (Luminal)FDA Link 11/2022 - 04/2016
5	A-Form DNA (A-DNA)IBA 01/2022 - 11/2018
5	Proto-Oncogene Proteins c-etsIBA 07/2013 - 01/2012
4	Glucose (Dextrose)FDA LinkGeneric 10/2022 - 01/2017
4	Cadherins (E-Cadherin)IBA 02/2022 - 09/2005
4	N-methyladenosineIBA 01/2022 - 03/2020
4	Protein Isoforms (Isoforms)IBA 01/2022 - 05/2005
4	6-methyladenineIBA 09/2021 - 12/2019
4	Decitabine FDA Link 01/2020 - 10/2006
4	Histone MethyltransferasesIBA 01/2017 - 01/2015
4	hydrogen sulfite (bisulfite)IBA 05/2014 - 03/2008
3	ProteomeIBA 10/2023 - 01/2021
3	ErbB Receptors (EGF Receptor)IBA 06/2023 - 08/2011
3	Hydralazine (Apresoline)FDA LinkGeneric 08/2021 - 08/2014
3	Prostate-Specific Antigen (Semenogelase)IBA 07/2020 - 10/2007
3	ParaffinIBA 04/2020 - 07/2007
3	NucleosidesIBA 01/2020 - 01/2014
3	Transcription Factors (Transcription Factor)IBA 11/2018 - 01/2011
3	Transforming Growth Factor-beta Type II ReceptorIBA 08/2015 - 10/2010
2	Long Noncoding RNAIBA 01/2024 - 01/2018
2	Hormones (Hormone)IBA 10/2023 - 11/2018
2	AndrogensIBA 10/2023 - 08/2021
2	VaccinesIBA 01/2023 - 12/2019
2	VimentinIBA 01/2023 - 01/2020
2	GuanineIBA 11/2022 - 01/2022
2	CytosineIBA 11/2022 - 01/2022
2	Phosphates (Orthophosphate)IBA 11/2022 - 01/2022
2	PlatinumIBA 06/2022 - 01/2020
2	flavanoneIBA 09/2021 - 01/2021
2	PanobinostatIBA 07/2021 - 10/2020
2	Tamoxifen FDA LinkGeneric 06/2021 - 11/2018
2	Telomerase (Telomerase Reverse Transcriptase)IBA 11/2020 - 06/2019
2	Histone Deacetylase InhibitorsIBA 10/2020 - 05/2011
2	SirtuinsIBA 04/2020 - 01/2020
2	Formaldehyde (Formol)FDA Link 04/2020 - 11/2019
2	Histone Deacetylases (Histone Deacetylase)IBA 01/2020 - 07/2015
2	Sirtuin 1IBA 01/2020 - 10/2013
2	AntibodiesIBA 11/2019 - 09/2011
2	Nonsense Codon (Nonsense Mutation)IBA 01/2019 - 02/2016
2	Volatile Organic CompoundsIBA 01/2018 - 01/2017
2	Calcibiotic Root Canal SealerIBA 12/2017 - 08/2015
2	Histone DemethylasesIBA 01/2017 - 01/2015

Therapy/Procedure

37	Therapeutics 12/2023 - 02/2004
7	Drug Therapy (Chemotherapy) 01/2023 - 09/2010
4	Radiotherapy 12/2020 - 01/2017
3	Neoadjuvant Therapy 05/2023 - 01/2022
3	Immunotherapy 01/2022 - 01/2021
3	Prostatectomy (Retropubic Prostatectomy) 10/2020 - 01/2006
2	Transplantation 10/2023 - 10/2007
2	Secondary Prevention 01/2023 - 01/2023